The authors conducted the clinical analysis on total 78 cases with acute CO poisoning and its neurological sequelae; 14 cases of acute CO poisoning and 13 cases with its sequelae, were admitted to St. Mary´s Hospital during past two years between Jan. 1967 and Nov. 1968. and 51 cases of acute CO poisoning treated at the emergency room between Jan. and Nov. 1968.
The following conclusions were made.
1) Chief complaints in acute CO poisoning were .drowsy mental state, semicoma, pink skin color, headache, nausea and vomiting in order, and those in patients with its sequelae the inability to control defecation and urination, disorientation, confusion, memory disturbance, aphasia and amnesia.
2) Recovery of full consciousness in acute CO poisoning was within 10 hours in 42 cases (65%) and within 24 hours in 11 (17%). Interval of symptomless period in patients with its sequelae after onset of acute CO poisoning was predominantly between 21 and 30 days, and none within 10 days or over 50 days.
3) In neurological examination, the most prominent signs were abnormality of D.T.R. and spasticity of the extremities in acute CO poisoning. and "cog-wheel" rigidity and tremor in Parkinsonism cases.
4) Prognosis in 65 patients acute CO poisoning was good in 60 (92%), and poor in 5 (8%); three of them were discharged hopelessly emergency room and two had bacterial infection secondary to severe burn injury. None in Parkinsonism had good prognosis and two died, one of renal failure and other of unknown origin. In psychosis; 3 patients remained unimproved and the 3 remainders were progressively worsen.
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